Anti Lamin A C Antibody

Western blot analysis of extracts of nci h293 cells using anti lamin a c antibody a0464. The expected protein mass is 74 1 kda but there are 6 reported isoforms. Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope.

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Rabbit Polyclonal Lamin A C Antibody Stj93885

Cleaved Lamin A Asp230 Antibody Cell Signaling Technology

Anti Lamina C Antibody Rabbit Lamin A C Polyclonal Antibody Np 001244303 1

Anti Lamin A Antibody Ab2559 Abcam

Anti Lamin A Lamin C Antibody Wl4g10 Ko Tested Ab232730 Abcam

Purified Anti Lamin A C Antibody Lamin A C Wl4g10

As a result this antibody recognizes lamin a but not lamin c.

Anti lamin a c antibody.

Performed under reducing conditions. Lamins a and c are alternatively spliced versions of the lmna gene. The protein may also be known as lamin c dhe lamin a cdcd1 cddc and cmd1a. In humans this protein is encoded by the gene lmna.

Lamin a c antibody 636 is a mouse monoclonal igg 2b kappa light chain provided at 200 µg ml. Anti lamin a c antibody e 1 is a mouse monoclonal igg 1 kappa light chain lamin a c antibody provided at 200 µg ml. This antibody has been reported by an independent laboratory to detect lamin a c in human endothelial cells. Raised against porcine lamin preparation.

Anti lamin a c antibodies are available from several suppliers. Peptide from human lamin a c corresponding to amino acids 398 to 490. 70 kda ab8984 was used at a 1 100 dilution against human fibroblast lysate. Since both dna blue and lamin a c red are associated with the nuclear compartment this region appears crimson in this image.

See machiels et al 1997. Lamin a and c are detected. Species predicted to react based on 100 sequence homology. Goat anti rabbit igg h l hrp as014 at 1 10 000 dilution.

The anti lamin a c antibody reveals strong nuclear lamina staining while anti lamp1 antibody reveals strong cytoplasmic punctate staining of lysosomes and early endosomes. Application anti lamin a c antibody clone 14 detects level of lamin a c has been published validated for use in ic wb. Specific for an epitope mapping between amino acids 2 29 at the n terminus of lamin a c of human origin. Anti lamin a c antibody 636 is recommended for detection of lamin a and lamin c of mouse rat and human origin by wb ip if ihc p and fcm.

Anti lamin a lamin c antibody 131c3 nuclear envelope marker ab8984 at 1 100 dilution human fibroblast cell lysate at 15 µl developed using the ecl technique. Lamin a c antibody detects endogenous levels of total full length lamin a and lamin c 70 kda as well as the small fragment of lamin a and lamin c resulting from cleavage at aspartic acid 230 28 kda. These proteins are found in many different cell types in three different forms a b and c. Reacts against lamin a exclusively the antibody was raised against the carboxy terminus of 98 amino acids present in lamin a and absent from lamin c.

Lamin a c antibodies.